Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
3-(4-Chlorophenoxy)pyrrolidine → N-(2-{3-[3-(4-Chlorophenoxy)-1-pyrrolidinyl]-2-hydroxy-2-methylpropoxy}phenyl)acetamide Hydrochloride
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 3-(4-Chlorophenoxy)pyrrolidine | HCID 12999570 | — |
| 반응물 | N-{2-[(2-methyl-2-oxiranyl)methoxy]phenyl}acetamide | HCID 22386946 | — |
| 생성물 | N-(2-{3-[3-(4-Chlorophenoxy)-1-pyrrolidinyl]-2-hydroxy-2-methylpropoxy}phenyl)acetamide Hydrochloride | HCID 22313690 | 221.3% |
반응 단계
The title compound (255 mg, 110%) was prepared from N-{2-[(2-methyl-2-oxiranyl)methoxy]phenyl}acetamide (123 mg, 0.557 mmol) and 3-(4-chlorophenoxy)pyrrolidine (100 mg, 0.506 mmol) analogously to that described in Example 1 (iii).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06943188B2 |
| 출처 데이터셋 | uspto-grants-2005_09 |
| ORD ID | ord-d7278182259647c5828a3666184ca99a |
| 출처 메모 | uspto-grants-2005_09 |