HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetamidomalonic acid diethyl ester → HCID 131725145, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetamidomalonic acid diethyl ester | HCID 14041 | — |
| Reactant | 3-Methyl-2-butenal | HCID 61020 | — |
| Product | HCID 131725145 | HCID 131725145 | 41.5% |
Reaction Steps
N-Acetyl-2-ethoxycarbonyl-3,3-dimethylproline, ethyl ester (6.4 g, 38%) was prepared from 3-methyl-2-butenal (Aldrich, 5.0 g, 59 mmol) and diethyl acetamidomalonate (Aldrich, 12 g, 54 mmol) by the procedure described by Chung et al (J. Org. Chem. 1990, 55, 270).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06943180B2 |
| Source dataset | uspto-grants-2005_09 |
| ORD ID | ord-130badaf1d2944deab5351d729f2611f |
| Source note | uspto-grants-2005_09 |