HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 10542617, compound → HCID 131725148, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 10542617 | HCID 10542617 | — |
| Catalyst | Adams' catalyst | HCID 345198 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 131725148 | HCID 131725148 | — |
Reaction Steps
A mixture of N-BOC-4(R)-phenyl-(L)-proline, methyl ester from Example 61, Step B (0.165 g, 0.54 mmol), PtO2 (0.1 g, 0.44 mmol) and MeOH was shaken under 50 psi of H2 overnight. The reaction was filtered through a pad of celite and concentrated in vacuo to afford N-BOC-4(R)-cyclohexyl-(L)-proline, methyl ester which was used without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06943180B2 |
| Source dataset | uspto-grants-2005_09 |
| ORD ID | ord-916a186461ca4f54add585d7174aaf13 |
| Source note | uspto-grants-2005_09 |