Hydrochloric Acid → HCID 69351593, compound

Participants

Reaction Steps

To a solution of 0.099 g of N-(BOC)-3,3-diallyl-4-oxo-(L)-proline, methyl ester in 0.4 mL of water and 1.6 mL of MeOH was added 25.7 mg of LiOH.monohydrate. The reaction mixture was sonicated for 2 h. The mixture was acidified with 1.2N HCl to pH=2 and concentrated in vacuo. The residue was treated with 1.5 mL of HCl/dioxane solution for 1.5 h. After concentration in vacuo, 0.12 g of 3,3-diallyl-4-oxo-(L)-proline was obtained which was used in the next step without purification.

Provenance & Evidence