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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 496357Generated: October 30, 2026

Thiomorpholine → N-[4-(5,6-dimethoxy-3-methyl-1,4-benzoquinon-2-ylmethyl)benzoyl]thiomorpholine

https://huagongshe.com/reaction/496357

Reaction equation

Participants

RoleNameHCIDCharge
ReactantThiomorpholineHCID 67164—
Reactant4-(5,6-Dimethoxy-3-methyl-1,4-benzoquinon-2-ylmethyl)benzoic acidHCID 9948816—
ProductN-[4-(5,6-dimethoxy-3-methyl-1,4-benzoquinon-2-ylmethyl)benzoyl]thiomorpholineHCID 982236651%

Reaction Steps

4-(5,6-dimethoxy-3-methyl-1,4-benzoquinon-2-ylmethyl)benzoic acid (100 mg, 0.32 mmol) obtained in Example 21 and thiomorpholine (0.035 ml, 0.35 mmol) were used, and a method similar to that described in Example 24 was employed to obtain the title compound (65 mg, 0.16 mmol, yield 51%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06943196B1
Source datasetuspto-grants-2005_09
ORD IDord-d6f32bc083b84e99803f8a8fd7d537d6
Source noteuspto-grants-2005_09