HuagongsheHuagongshe Chemistry Print Report · For research reference only
(+-)-2-Butanol → (+/-)5-sec-Butoxymethyl-6-hydroxy-3,4-dihydro-2H-naphthalen-1-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (+-)-2-Butanol | HCID 6568 | — |
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 5-(chloromethyl)-6-hydroxy-3,4-dihydro-1(2H)-naphthalenone | HCID 12393619 | — |
| Product | (+/-)5-sec-Butoxymethyl-6-hydroxy-3,4-dihydro-2H-naphthalen-1-one | HCID 22325010 | — |
Reaction Steps
According to step (a) in the method of example A, 5-Chloromethyl-6-hydroxy-3,4-dihydro-2H-naphthalen-1-one (0.211 g, 1.0 mmol) was combined with triethylamine (0.167 ml, 1.2 mmol) in (±)butan-2-ol (3 ml, Aldrich Chemical) to produce 159 mg of desired product as an orange oil. Low resolution mass spectrum (APCI) m/z 249 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06943183B2 |
| Source dataset | uspto-grants-2005_09 |
| ORD ID | ord-e7d7ec0f7d0f40668d20c5af8cc9866a |
| Source note | uspto-grants-2005_09 |