Hydrochloric Acid → HCID 22324981, compound

Participants

Reaction Conditions

Reaction Steps

4-(3-Chlorophenyl)-6-methoxy-1-tetralone (0.85 g, 3 mmol) is dissolved in DMSO (10 mL). Crushed NaCN (0.73 g, 15 mmol) is added, and the reaction is heated at 180° C. overnight. The reaction is then poured into water (70 mL) and acidified to pH 2 using concentrated HCl. The resulting brown solid (0.8 g, 100% yield) is filtered and dried in a vacuum oven at 50° C. for 2 hours.

Provenance & Evidence