HCID 22324945, compound → HCID 20828854, compound

HRID 496433Notes

Reaction equation

HRID 496433 reaction equation
[OH:1][C:2]1[C:3]([CH2:13][S:14]([C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][N:18]=2)(=[O:16])=[O:15])=[C:4]2[C:9](=[CH:10][CH:11]=1)[C:8](=[O:12])[CH2:7][CH2:6][CH2:5]2.[F:23][C:24]1[CH:29]=[C:28]([F:30])[CH:27]=[CH:26][C:25]=1[C@@H:31](O)[CH2:32][N:33]1[CH:37]=[CH:36][N:35]=[CH:34]1>>[F:23][C:24]1[CH:29]=[C:28]([F:30])[CH:27]=[CH:26][C:25]=1[C@H:31]([O:1][C:2]1[C:3]([CH2:13][S:14]([C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][N:18]=2)(=[O:16])=[O:15])=[C:4]2[C:9](=[CH:10][CH:11]=1)[C:8](=[O:12])[CH2:7][CH2:6][CH2:5]2)[CH2:32][N:33]1[CH:37]=[CH:36][N:35]=[CH:34]1

Participants

3

Reactant 2

HCID 22324945HCID 22324945, compoundHCID 60029925HCID 60029925, compound

Product 1

HCID 20828854HCID 20828854, compound

Procedure

The title compound was prepared using the procedure of Example 10, step (b) using 6-Hydroxy-5-(pyridine-2-sulfonylmethyl)-3,4-dihydro-2H-naphthalen-1-one and (R)-1-(2,4-difluoro-phenyl)-2-Imidazol-1-yl-ethanol.

Sources & evidence

ORD record
ord-a658cf516dc943f7aa71f32bff466db8
Source dataset
uspto-grants-2005_09
Patent number
US06943183B2

Reaction notes

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