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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 496452Generated: October 30, 2026

Ethanolamine → HCID 69737053, compound

https://huagongshe.com/reaction/496452

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthanolamineHCID 700—
Reactant2-{[(2-{[(1S)-2-(1H-imidazol-yl)-1-phenylethyl]oxy}-5-oxo-5,6,7,8-tetrahydro-1-naphthalenyl)methyl]sulfanyl}benzoic acidHCID 69735263—
ProductHCID 69737053HCID 6973705355.4%

Reaction Steps

Using the method in Example 172, 2-{[(2-{[(1S)-2-(1H-imidazol-1-yl)-1-phenylethyl]oxy}-5-oxo-5,6,7,8-tetrahydro-1-naphthalenyl)methyl]sulfanyl}benzoic acid (50 mg, 0.10 mmol, 0.20M in DMF) and 2-aminoethanol (31 mg, 0.50 mmol, 1.0M in DMF) were combined to give 30 mg of the desired compound: Low resolution mass spectrum (LC-MS, APCI) m/z 542 [M+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06943183B2
Source datasetuspto-grants-2005_09
ORD IDord-948f5fa5a0ac441492f7d55a84e47520
Source noteuspto-grants-2005_09