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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 496490Generated: October 30, 2026

Cyclopropylamine → HCID 69736870, compound

https://huagongshe.com/reaction/496490

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCyclopropylamineHCID 69828—
Reactant4-{[(2-{[(1S)-2-(1H-imidazol-1-yl)-1-phenylethyl]oxy}-5-oxo-5,6,7,8-tetrahydro-1-naphthalenyl)methyl]sulfanyl}benzoic acidHCID 60029877—
ProductHCID 69736870HCID 6973687087.4%

Reaction Steps

Using the method in Example 172, 4-{[(2-{[(1S)-2-(1H-imidazol-1-yl)-1-phenylethyl]oxy}-5-oxo-5,6,7,8-tetrahydro-1-naphthalenyl)methyl]sulfanyl}benzoic acid (50 mg, 0.10 mmol, 0.20M in DMF) and cyclopropylamine (17 mg, 0.30 mmol, 0.6M in DMF) were combined to give 47 mg of the desired compound: Low resolution mass spectrum (LC-MS, APCI) m/z 538 [M+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06943183B2
Source datasetuspto-grants-2005_09
ORD IDord-f42744a1959b47a58fef09d33fa0e7e1
Source noteuspto-grants-2005_09