HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Amino-2-propanol → HCID 69737008, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Amino-2-propanol | HCID 4 | — |
| Reactant | 4-{[(2-{[(1S)-2-(1H-imidazol-1-yl)-1-phenylethyl]oxy}-5-oxo-5,6,7,8-tetrahydro-1-naphthalenyl)methyl]sulfanyl}benzoic acid | HCID 60029877 | — |
| Product | HCID 69737008 | HCID 69737008 | 82.8% |
Reaction Steps
Using the method in Example 172, 4-{[(2-{[(1S)-2-(1H-imidazol-1-yl)-1-phenylethyl]oxy}-5-oxo-5,6,7,8-tetrahydro-1-naphthalenyl)methyl]sulfanyl}benzoic acid (50 mg, 0.10 mmol, 0.20M in DMF) and 1-amino-2-propanol (23 mg, 0.30 mmol, 0.6M in DMF) were combined to give 46 mg of the desired compound: Low resolution mass spectrum (LC-MS, APCI) m/z 556 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06943183B2 |
| Source dataset | uspto-grants-2005_09 |
| ORD ID | ord-6dcf1f3f90eb431c8ad9ec986f37e864 |
| Source note | uspto-grants-2005_09 |