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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 496516Generated: October 30, 2026

1-Amino-2-propanol → HCID 69736964, compound

https://huagongshe.com/reaction/496516

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Amino-2-propanolHCID 4—
Reactant2-{[(2-{[(1S)-2-(1H-imidazol-yl)-1-phenylethyl]oxy}-5-oxo-5,6,7,8-tetrahydro-1-naphthalenyl)methyl]sulfanyl}benzoic acidHCID 69735263—
ProductHCID 69736964HCID 6973696457.6%

Reaction Steps

Using the method in Example 172, 2-{[(2-{[(1S)-2-(1H-imidazol-yl)-1-phenylethyl]oxy}-5-oxo-5,6,7,8-tetrahydro-1-naphthalenyl)methyl]sulfanyl}benzoic acid (50 mg, 0.10 mmol, 0.20M in DMF) and 1-amino-2-propanol (23 mg, 0.30 mmol, 0.6M in DMF) were combined to give 32 mg of the desired compound: Low resolution mass spectrum (LC-MS, APCI) m/z 556 [M+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06943183B2
Source datasetuspto-grants-2005_09
ORD IDord-e534ddbe5c254668a09e4f8fb1cbd97e
Source noteuspto-grants-2005_09