HCID 86594464, compound → HCID 69742386, compound

HRID 496526Notes

Reaction equation

HRID 496526 reaction equation
[Cl-:1].[CH3:2][N+:3]1[CH:7]=[CH:6][N:5]([CH:8]2[CH2:12][CH2:11][N:10]([C:13]3[CH:18]=[CH:17][C:16]([N+:19]([O-])=O)=[C:15](C)[CH:14]=3)[CH2:9]2)[CH:4]=1>C(O)C.[Pd]>[ClH:1].[Cl-:1].[CH3:2][NH+:3]1[CH:7]=[CH:6][N:5]([CH:8]2[CH2:12][CH2:11][N:10]([C:13]3[CH:18]=[CH:17][C:16]([NH2:19])=[CH:15][CH:14]=3)[CH2:9]2)[CH2:4]1

Participants

4

Reactant 1

HCID 86594464HCID 86594464, compound

Product 1

HCID 69742386HCID 69742386, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

3.2 g (0.01 mole) of derivative (4) in 300 ml of ethanol were hydrogenated in the presence of palladium on charcoal under hydrogen pressure of 9 bars. The catalyst was removed by filtration. The derivative (5) was isolated under chloride form.

Workup

  1. customThe catalyst was removed by filtration

Sources & evidence

ORD record
ord-3826b56849214f4c88889a1d16c4ccc8
Source dataset
uspto-grants-2005_09
Patent number
US06946005B2

Reaction notes

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