HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonia → 5-Amino-3,4-dihydronaphthalen-1(2H)-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | Sulfuric Acid | HCID 1118 | — |
| Reactant | 4-(2-Aminophenyl)butyronitrile | HCID 18405824 | — |
| Product | 5-Amino-3,4-dihydronaphthalen-1(2H)-one | HCID 11506505 | — |
Reaction Conditions
| Temperature | 100 °C |
|---|
Reaction Steps
In a 20 ml Schlenk vessel, 1 g of 96% sulfuric acid (9.79 mmol) is added to 100 mg of 4-(2-aminophenyl)butyronitrile (0.62 mmol) under argon. The mixture is heated to 100° C. for 66 h, stirring. After cooling, it is neutralised with aqueous ammonia solution (ice cooling), and the product is then extracted with chloroform and identified using GC.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06706924B2 |
| Source dataset | uspto-grants-2004_03 |
| ORD ID | ord-a8a01279e9524fbab2b2b0eb6ff5f636 |
| Source note | uspto-grants-2004_03 |