HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethylformamide → 2,3-Dimethoxybenzoyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethylformamide | HCID 6228 | — |
| Reactant | 2,3-Dimethoxybenzoic acid | HCID 15204 | — |
| Reactant | Oxalyl chloride | HCID 65578 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 2,3-Dimethoxybenzoyl chloride | HCID 2758392 | 90% |
Reaction Steps
To a solution of 2,3-dimethoxybenzoic acid (10.9781 mmol, 2.0 g) in CH2Cl2 (20 mL) with a drop of DMF, was added oxalyl chloride (10.9781 mmol, 957.702:1) dropwise at RT After 2 hrs the reaction mixture was concentrated in vacuo to afford 2,3-dimethoxybenzoyl chloride (1.9 g, 90%):
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06949534B2 |
| Source dataset | uspto-grants-2005_09 |
| ORD ID | ord-b7113f75830648d09e5bcf2d252a240d |
| Source note | uspto-grants-2005_09 |