HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phosphorus oxychloride → 6-Chloro-3-(isoxazol-3-yl)-imidazo[5,1-a]phthalazine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phosphorus oxychloride | HCID 24813 | — |
| Reactant | Isoxazol-3-carboxylic acid (4-oxo-3,4-dihydrophthalazin-1-ylmethyl)amide | HCID 86593723 | — |
| Product | 6-Chloro-3-(isoxazol-3-yl)-imidazo[5,1-a]phthalazine | HCID 22318516 | — |
Reaction Steps
The title compound was prepared from isoxazol-3-carboxylic acid (4-oxo-3,4-dihydrophthalazin-1-ylmethyl)amide (Part a) and phosphorus oxychloride according the procedure described in Example 1, Part b. 1H NMR (360 MHz, CDCl3) δ 7.25 (s, 1H), 7.66 (t, J=8 Hz, 1H), 7.86 (t, J=8 Hz, 1H), 7.97 (brs, 1H), 8.09 (d, J=8 Hz, 1H), 8.21 (d, J=8 Hz, 1H), 8.57 (d, J=2 Hz, 1H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06949549B2 |
| Source dataset | uspto-grants-2005_09 |
| ORD ID | ord-26ac49f3e43c49098bc0b3d46bf62309 |
| Source note | uspto-grants-2005_09 |