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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 49707Generated: October 29, 2026

HCID 18188087, compound → t-Butyl 4-amino-3-hydroxy-5-methyl-phenylacetate

https://huagongshe.com/reaction/49707

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 18188087HCID 18188087—
CatalystPalladiumHCID 23938—
SolventEthanolHCID 702—
Productt-Butyl 4-amino-3-hydroxy-5-methyl-phenylacetateHCID 1818809591.1%

Reaction Steps

A solution of t-butyl 3-hydroxy-5-methyl-4-nitrophenylacetate (0.47 g, Reference Example 11) in ethanol (25 mL) was treated with palladium on charcoal (approximately 0.08 g, 10%) and stirred under a hydrogen atmosphere. After 4 hours the mixture was filtered through a pad of celite and the filtrate was evaporated to give the title compound (0.38 g) as a green oil.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06706738B2
Source datasetuspto-grants-2004_03
ORD IDord-edd0b289e01046f79badea7eddcd0376
Source noteuspto-grants-2004_03