HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 18188087, compound → t-Butyl 4-amino-3-hydroxy-5-methyl-phenylacetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 18188087 | HCID 18188087 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | t-Butyl 4-amino-3-hydroxy-5-methyl-phenylacetate | HCID 18188095 | 91.1% |
Reaction Steps
A solution of t-butyl 3-hydroxy-5-methyl-4-nitrophenylacetate (0.47 g, Reference Example 11) in ethanol (25 mL) was treated with palladium on charcoal (approximately 0.08 g, 10%) and stirred under a hydrogen atmosphere. After 4 hours the mixture was filtered through a pad of celite and the filtrate was evaporated to give the title compound (0.38 g) as a green oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06706738B2 |
| Source dataset | uspto-grants-2004_03 |
| ORD ID | ord-edd0b289e01046f79badea7eddcd0376 |
| Source note | uspto-grants-2004_03 |