HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → (RS) 3-(6-amino-pyrid-3-yl)-butanoic acid hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | (RS) ethyl 3-(6-acetylamino-pyrid-3-yl)-butanoate | HCID 17946644 | — |
| Product | (RS) 3-(6-amino-pyrid-3-yl)-butanoic acid hydrochloride | HCID 69687733 | — |
Reaction Steps
A solution of (RS) ethyl 3-(6-acetylamino-pyrid-3-yl)-butanoate (25.56 g, Reference Example 21) in aqueous hydrochloric acid (500 mL, 6M) was heated at 100° C. for 3.5 hours, then cooled and then evaporated to give the title compound as a crystalline solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06706738B2 |
| Source dataset | uspto-grants-2004_03 |
| ORD ID | ord-6982c1d35e444c62b2ca924c5617f84e |
| Source note | uspto-grants-2004_03 |