反应详情

To a stirred solution of 1-(4-bromo-2-methoxyphenyl)-1-ethanone (31.5 g, 138 mmol) in dioxane (32 ml) was added a solution of bromine (21.8 g, 136 mmol) in dioxane (123 ml), and the mixture was stirred for 3 hours. Then the volatile was evaporated in vacuo. The residue was recrystallized with hexane-dichloromethane to give title compound (32.1 g, 76% yield).

1. customThen the volatile was evaporated in vacuo
2. customThe residue was recrystallized with hexane-dichloromethane