HCID 22313821, compound → HCID 22316690, compound

HRID 497246Notes

Reaction equation

HRID 497246 reaction equation
Cl.[F:2][C:3]1[CH:8]=[C:7]([S:9](=[O:12])(=[O:11])[NH2:10])[CH:6]=[CH:5][C:4]=1[NH:13][NH2:14].[F:15][C:16]([F:35])([F:34])[C:17](=O)[CH2:18][C:19]([C:21]1[CH:26]=[CH:25][C:24]([C:27]2[N:28]=[CH:29][S:30][CH:31]=2)=[C:23]([CH3:32])[CH:22]=1)=O>>[F:2][C:3]1[CH:8]=[C:7]([S:9]([NH2:10])(=[O:12])=[O:11])[CH:6]=[CH:5][C:4]=1[N:13]1[C:19]([C:21]2[CH:26]=[CH:25][C:24]([C:27]3[N:28]=[CH:29][S:30][CH:31]=3)=[C:23]([CH3:32])[CH:22]=2)=[CH:18][C:17]([C:16]([F:35])([F:34])[F:15])=[N:14]1

Participants

3

Reactant 2

HCID 22313821HCID 22313821, compoundHCID 22316599HCID 22316599, compound

Product 1

HCID 22316690HCID 22316690, compound

Procedure

The title compound was prepared according to the procedure of Example 60 using 2-fluoro-4-sulfamoylphenylhydrazine hydrochloride instead of 3-fluoro-4-(methylsulfonyl)phenylhydrazine hydrochloride and 4,4,4-trifluoro-1-[3-methyl-4-(4-thiazolyl)phenyl]butane-1,3-dione instead of 4,4,4-trifluoro-1-[4-(2-furyl)phenyl]butane-1,3-dione in step 2.

Sources & evidence

ORD record
ord-924a613e22e246b4bbd809017311793d
Source dataset
uspto-grants-2005_09
Patent number
US06949536B2

Reaction notes

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