HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Chloro-4-(methylsulfonyl)phenylhydrazine hydrochloride → 1-[3-Chloro-4-(methylsulfonyl)phenyl]-5-[4-(4-thiazolyl)phenyl]-3-trifluoromethyl-1H-pyrazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Chloro-4-(methylsulfonyl)phenylhydrazine hydrochloride | HCID 22316873 | — |
| Reactant | 4,4,4-Trifluoro-1-[4-(4-thiazolyl)phenyl]butane-1,3-dione | HCID 22316915 | — |
| Product | 1-[3-Chloro-4-(methylsulfonyl)phenyl]-5-[4-(4-thiazolyl)phenyl]-3-trifluoromethyl-1H-pyrazole | HCID 22316911 | — |
Reaction Steps
The title compound was prepared according to the procedure of Example 60 using [3-chloro-4-(methylsulfonyl)phenyl]hydrazine hydrochloride from step 1 of Example 155 instead of [3-fluoro-4-(methylsulfonyl)phenyl]hydrazine hydrochloride, 4,4,4-trifluoro-1-[4-(1,3-thiazol-4-yl)phenyl]-1,3-butanedione from step 3 of Example 82 instead of 4,4,4-trifluorro-1-[4-(2-furyl)phenyl]-1,3-butanedione.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06949536B2 |
| Source dataset | uspto-grants-2005_09 |
| ORD ID | ord-bb1acdafdf80444b8031e6c682212ab4 |
| Source note | uspto-grants-2005_09 |