Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 497252Generated: October 30, 2026

3-Chloro-4-(methylsulfonyl)phenylhydrazine hydrochloride → 1-[3-Chloro-4-(methylsulfonyl)phenyl]-5-[4-(4-thiazolyl)phenyl]-3-trifluoromethyl-1H-pyrazole

https://huagongshe.com/reaction/497252

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Chloro-4-(methylsulfonyl)phenylhydrazine hydrochlorideHCID 22316873—
Reactant4,4,4-Trifluoro-1-[4-(4-thiazolyl)phenyl]butane-1,3-dioneHCID 22316915—
Product1-[3-Chloro-4-(methylsulfonyl)phenyl]-5-[4-(4-thiazolyl)phenyl]-3-trifluoromethyl-1H-pyrazoleHCID 22316911—

Reaction Steps

The title compound was prepared according to the procedure of Example 60 using [3-chloro-4-(methylsulfonyl)phenyl]hydrazine hydrochloride from step 1 of Example 155 instead of [3-fluoro-4-(methylsulfonyl)phenyl]hydrazine hydrochloride, 4,4,4-trifluoro-1-[4-(1,3-thiazol-4-yl)phenyl]-1,3-butanedione from step 3 of Example 82 instead of 4,4,4-trifluorro-1-[4-(2-furyl)phenyl]-1,3-butanedione.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06949536B2
Source datasetuspto-grants-2005_09
ORD IDord-bb1acdafdf80444b8031e6c682212ab4
Source noteuspto-grants-2005_09