反应详情

A solution of 5.00 g (1 eq.) of 4-chlorosulfonylphenylisocyanate in anhydrous DCM (40 ml) was added to a solution of 3-aminobenzonitrile (2.71 g, 1 eq.) in anhydrous isocyanate (60 ml) at rt under inert atmosphere and the mixture was stirred overnight. The precipitate was filtered off to yield 7.3 g (95%) of 4-[3-(3-cyanophenyl)-ureido]-benzenesulfonyl chloride.

1. filtrationThe precipitate was filtered off