Mcl-0042 → HCID 9917300, compound

Participants

Reaction Steps

0.30 g of 1-[2-(4-Fluorophenyl)-2-(4-methylpiperazino)ethyl]-4-(4-naphthalen-1-yl-butyl)piperazine was dissolved in 4 ml of methanol, and 1 ml of 4M hydrogen chloride/ethyl acetate solution was added. The solution was concentrated under reduced pressure, and the resulting solid was washed with methanol to give 1-[2-(4-fluorophenyl)-2-(4-methylpiperazino)ethyl]-4-(4-naphthalen-1-yl-butyl)piperazine tetrahydrochloride (0.20 g).

Provenance & Evidence