HCID 10098971, compound → HCID 22318629, compound

Participants

Reaction Steps

0.12 g of (+)-1-[2-(4-Fluorophenyl)-2-(4-isopropylpiperazino)ethyl]-4-[4-(2-methoxynaphthalen-1-yl)butyl]piperazine was dissolved in 4 ml of methanol, and 1 ml of 4M hydrogen chloride/ethyl acetate solution was added. After concentration under reduced pressure, the resulting solid was washed with ethyl acetate to give 0.12 g of (+)-1-[2-(4-fluorophenyl)-2-(4-isopropylpiperazino)ethyl]-4-[4-(2-methoxynaphthalen-1-yl)butyl]piperazine tetrahydrochloride.

Provenance & Evidence