HCID 22318750, compound → HCID 22318798, compound

Participants

Reaction Steps

A mixture of 321 mg (1.75 mmol) of (2-dimethoxymethyl-pyridin-3-yl)-methanol and 763 mg (8.77 mmol) of MnO2 in 10 mL of toluene is refluxed for 1.5 hours. The reaction mixture is cooled to room temperature and filtered. The filtrate is evaporated to yield 271 mg of 2-dimethoxymethyl-pyridine-3-carbaldehyde. 1H NMR (CDCl3) δ 10.30 (s, 1H), 8.30 (d, 1H), 8.10 (d, 1H), 7.30 (m, 1H), 5.40 (s, 2H), 4.40 (s, 6H). Step 5:

Provenance & Evidence