HCID 22645922, Verbindung → 3,3,4,4-Tetrafluoropyrrolidine Hydrochloride

Beteiligte Stoffe

Reaktionsschritte

A solution of 1-benzyl-3,3,4,4-tetrafluoro-pyrrolidine hydrochloride (23.8 g, 88 mmol) in ethanol (300 mL) containing 10% palladium on carbon was treated with hydrogen in a Parr shaker at 45 psi for 3 hours. The mixture was filtered through Celite®, the filtrate was concentrated to dryness. The residue was triturated with ether and the solid was collected and dried (13.4 g, 85%, (mp 193-196° C.).

Herkunft & Nachweise