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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 497721Generated: October 28, 2026

5-Hexyn-1-ol → HCID 86595615, compound

https://huagongshe.com/reaction/497721

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Hexyn-1-olHCID 70234—
Reactant1-{5-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-2-deoxypentofuranosyl}-4-hydroxypyrimidin-2(1H)-oneHCID 90230—
ProductHCID 86595615HCID 8659561586%

Reaction Steps

5-Hexynol was allowed to react with 2′-deoxy-5′-O-(4,4′-dimethoxytrityl)uridine under Mitsunobu conditions described in example 1. Purification on silica gel (eluent diethyl ether) yielded the title compound as a solid (86%) Compound 9:

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06949639B1
Source datasetuspto-grants-2005_09
ORD IDord-9ab14dc55d284e1485bad44f030fd1e1
Source noteuspto-grants-2005_09