돌아가기
Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 497724생성일: 2026년 10월 25일

1-(Bromomethyl)-2,3-difluoro-benzene → HCID 178508256, 화합물

https://huagongshe.com/reaction/497724

반응식

참여 물질

역할이름HCID투입량
반응물1-(Bromomethyl)-2,3-difluoro-benzeneHCID 517984—
반응물2-amino-5,6-dihydro-5-thioxo-thiazolo[4,5-d]pyrimidin-7(4H)-oneHCID 11458309—
반응물Potassium tert-butoxideHCID 23665647—
용매Dimethyl SulfoxideHCID 679—
생성물HCID 178508256HCID 178508256—

반응 단계

Potassium t-butoxide solution (0.45 ml of 1M solution in tetrahydrofuran) was added to a stirred solution of 2-amino-5,6-dihydro-5-thioxo-thiazolo[4,5-d]pyrimidin-7(4H)-one (0.09 g) [Cited: Indian J. Chem., Sect. B (1989), 28B(11), 964-5.] and 2,3-difluorobenzyl bromide in dimethyl sulphoxide (2 ml). After stirring for 3 days, the reaction mixture was poured onto water to give the subtitled compound, isolated by filtration.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US06949643B2
출처 데이터셋uspto-grants-2005_09
ORD IDord-b6a347acda6b4dbca61ecd344191ad1d
출처 메모uspto-grants-2005_09