HuagongsheHuagongshe Chemistry Print Report · For research reference only
Picolyl chloride → 4-Chloro-3-methyl-1-(2-pyridinylmethyl)-1H-pyrazolo[3,4-b]quinoline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Picolyl chloride | HCID 23393 | — |
| Reactant | 2-(2-Oxo-propyl)-benzo[D][1,3]oxazin-4-one | HCID 15938097 | — |
| Reactant | 2-(Hydrazinylmethyl)pyridine | HCID 16228721 | — |
| Product | 4-Chloro-3-methyl-1-(2-pyridinylmethyl)-1H-pyrazolo[3,4-b]quinoline | HCID 22320100 | — |
Reaction Steps
Following the procedures described in Reference Example 1-10 and Example 1-34, the title compound was prepared from 2-(2-oxopropyl)-4H-3,1-benzoxazin-4-one and 2-hydrazinomethylpyridine which was separately prepared from 2-chloromethylpyridine following the method described in Reference Example 1-9 (75% yield).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06949648B2 |
| Source dataset | uspto-grants-2005_09 |
| ORD ID | ord-fd12e5214e954f5f8bd114daae15d1bd |
| Source note | uspto-grants-2005_09 |