Thiophenol → 5-Bromo-2-chloro-4-(phenylthio)pyrimidine

反応式

[Br:1][C:2]1[C:3](Cl)=[N:4][C:5]([Cl:8])=[N:6][CH:7]=1.[C:10]1([SH:16])[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1>>[Br:1][C:2]1[C:3]([S:16][C:10]2[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=2)=[N:4][C:5]([Cl:8])=[N:6][CH:7]=1

参加物

反応物 2

HCID 7969Thiophenol

HCID 2899735-Bromo-2,4-dichloropyrimidine

生成物 1

HCID 790726395-Bromo-2-chloro-4-(phenylthio)pyrimidine

実験手順

Using an analogous method to that described in Method 1, but starting from 5-bromo-2,4-dichloropyrimidine and thiophenol, the product was obtained. NMR: 7.6 (m, 5H), 8.8 (s, 1H).

後処理

customthe product was obtained

出典と根拠

ORDレコード: ord-99b646fbcedb4fa08746bae593920360
出典データセット: uspto-grants-2004_03
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US06710052B2

反応ノート

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