HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloroquinoline → 4-Chloro-3,8-dimethyl-1-(2-quinolinyl)-1H-pyrazolo[3,4-b]quinoline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloroquinoline | HCID 11928 | — |
| Reactant | Quinoline, 2-hydrazinyl- | HCID 85111 | — |
| Reactant | 8-methyl-2-(2-oxopropyl)-4H-3,1-benzoxazin-4-one | HCID 22320304 | — |
| Product | 4-Chloro-3,8-dimethyl-1-(2-quinolinyl)-1H-pyrazolo[3,4-b]quinoline | HCID 22320348 | — |
Reaction Steps
Following the procedure described in Reference Example 2-3 and Example 2-1, the title compound was prepared from 8-methyl-2-(2-oxopropyl)-4H-3,1-benzoxazin-4-one and 2-hydrazinoquinoline which was previously prepared form 2-chloroquinoline following the method described in Reference Example 2-2 (42% yield).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06949648B2 |
| Source dataset | uspto-grants-2005_09 |
| ORD ID | ord-96aeddbf6a9b4492bdf75d126f24836a |
| Source note | uspto-grants-2005_09 |