HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Iodobenzoic acid → 3-Phenyl-1-(2-pyridinyl)-1,9-dihydro-4H-pyrazolo[3,4-b]quinolin-4-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Iodobenzoic acid | HCID 6941 | — |
| Reactant | Benzoylacetonitrile | HCID 64799 | — |
| Reactant | 2-Hydrazinopyridine | HCID 78645 | — |
| Reactant | 1-pyridyl-3-phenyl-5-aminopyrazole | HCID 12288136 | — |
| Product | 3-Phenyl-1-(2-pyridinyl)-1,9-dihydro-4H-pyrazolo[3,4-b]quinolin-4-one | HCID 135848072 | — |
Reaction Steps
Following the procedures described in Reference Example 2-5 and Example 2-12, the title compound was prepared from o-iodobenzoic acid and 3-phenyl-1-(2-pyridinyl)-1H-pyrazol-5-ylamine which was previously prepared from benzoylacetonitrile and 2-hydrazinopyridine following the method described in Reference Example 2-72 (58% yield).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06949648B2 |
| Source dataset | uspto-grants-2005_09 |
| ORD ID | ord-2d0d0910f2d34f18aedcdc96b631b276 |
| Source note | uspto-grants-2005_09 |