HCID 12080904, compound → 5-Ethynylisophthalic acid

HRID 498157Notes

Reaction equation

HRID 498157 reaction equation
[C:1]([C:3]1[CH:4]=[C:5]([C:12]([O-:14])=[O:13])[CH:6]=[C:7]([CH:11]=1)[C:8]([O-:10])=[O:9])#[CH:2].[K+].[K+]>O>[C:1]([C:3]1[CH:4]=[C:5]([C:12]([OH:14])=[O:13])[CH:6]=[C:7]([CH:11]=1)[C:8]([OH:10])=[O:9])#[CH:2]

Participants

3

Reactant 1

HCID 12080904HCID 12080904, compound

Product 1

HCID 120809055-Ethynylisophthalic acidYield 99.5%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

Dipotassium 5-ethynylisophthalate in an amount of 5 g (0.019 moles) was dissolved into 20 ml of ion-exchanged water and insoluble substances were removed by filtration with a 5C filter paper. To the obtained filtrate, a 5 moles/liter hydrochloric acid was added under stirring until the pH became 1. The formed solid substance was separated by filtration, washed with ion-exchanged water and filtered. The filtration and the washing were repeated twice. The obtained solid substance was dried at 50° C. under a reduced pressure and 3.6 g of 5-ethynylisophthalic acid was obtained (the yield: 99.5%).

Workup

  1. customwere removed by filtration with a 5C
  2. filtrationfilter paper
  3. additionTo the obtained filtrate, a 5 moles/liter hydrochloric acid was added
  4. customThe formed solid substance was separated by filtration
  5. washwashed with ion-exchanged water
  6. filtrationfiltered
  7. filtrationThe filtration
  8. customThe obtained solid substance was dried at 50° C. under a reduced pressure

Sources & evidence

ORD record
ord-07eaffbab5934c26998901ecd7cf5333
Source dataset
uspto-grants-2005_09
Patent number
US06949674B2

Reaction notes

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