HuagongsheHuagongshe Chemistry Print Report · For research reference only
Isobutylamine → (4-Chloro-5-isobutylamino-2-nitro-phenyl)-carbamic acid tert-butyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Isobutylamine | HCID 6558 | — |
| Reactant | HCID 69489445 | HCID 69489445 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Product | (4-Chloro-5-isobutylamino-2-nitro-phenyl)-carbamic acid tert-butyl ester | HCID 69489292 | — |
Reaction Steps
The title compound was prepared from (4,5-dichloro-2-nitro-phenyl)-carbamic acid tert-butyl ester (Example A20) (3.0 g, 9.77 mmol) and isobutylamine (3.57 g, 48.8 mmol) in DMSO (20 mL) at 55° C. according to the general procedure C. Obtained as a brown solid (2.26 g, 67%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06949542B2 |
| Source dataset | uspto-grants-2005_09 |
| ORD ID | ord-d39f250d4a7e4b7aae8d7e5860e387f7 |
| Source note | uspto-grants-2005_09 |