HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-Methylisobutylamine → [4-Chloro-5-(isobutyl-methyl-amino)-2-nitro-phenyl]-carbamic acid tert-butyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-Methylisobutylamine | HCID 12249 | — |
| Reactant | HCID 69489445 | HCID 69489445 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Product | [4-Chloro-5-(isobutyl-methyl-amino)-2-nitro-phenyl]-carbamic acid tert-butyl ester | HCID 69489728 | — |
Reaction Steps
The title compound was prepared from (4,5-dichloro-2-nitro-phenyl)-carbamic acid tert.-butyl ester (Example A20) (5.0 g, 16.3 mmol) and N-isobutyl-methylamine (7.09 g, 81.4 mmol) in DMSO (50 mL) at RT according to the general procedure C. Obtained as a brown oil (5.79 g, 99%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06949542B2 |
| Source dataset | uspto-grants-2005_09 |
| ORD ID | ord-5e918677ead348acaaf6d6fa03c6ce10 |
| Source note | uspto-grants-2005_09 |