HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-Methylisopropylamine → [4-Chloro-5-(isopropyl-methyl-amino)-2-nitro-phenyl]-carbamic acid tert-butyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-Methylisopropylamine | HCID 78485 | — |
| Reactant | HCID 69489445 | HCID 69489445 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Product | [4-Chloro-5-(isopropyl-methyl-amino)-2-nitro-phenyl]-carbamic acid tert-butyl ester | HCID 69489449 | — |
Reaction Steps
The title compound was prepared from (4,5-dichloro-2-nitro-phenyl)-carbamic acid tert.-butyl ester (Example A20) (5.0 g, 16.3 mmol) and N-isopropyl-methylamine (5.95 g, 81.4 mmol) in DMSO (50 mL) at 75° C. according to the general procedure C. Obtained as a yellow solid (4.07 g, 73%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06949542B2 |
| Source dataset | uspto-grants-2005_09 |
| ORD ID | ord-f838b531b0e8417f92b39f08ca481824 |
| Source note | uspto-grants-2005_09 |