(5-Ethoxy-2-nitro-phenyl)-carbamic acid tert-butyl ester → HCID 69486521, compound

HRID 498201Notes

Reaction equation

HRID 498201 reaction equation
[C:1]([O:5][C:6](=[O:20])[NH:7][C:8]1[CH:13]=[C:12]([O:14][CH2:15][CH3:16])[CH:11]=[CH:10][C:9]=1[N+:17]([O-])=O)([CH3:4])([CH3:3])[CH3:2]>[Pd]>[C:1]([O:5][C:6](=[O:20])[NH:7][C:8]1[CH:13]=[C:12]([O:14][CH2:15][CH3:16])[CH:11]=[CH:10][C:9]=1[NH2:17])([CH3:3])([CH3:2])[CH3:4]

Participants

3

Reactant 1

HCID 69486672(5-Ethoxy-2-nitro-phenyl)-carbamic acid tert-butyl ester

Product 1

HCID 69486521HCID 69486521, compound

Reagents, catalysts & solvents 1

HCID 23938PalladiumCatalyst

Procedure

The title compound was prepared from (5-ethoxy-2-nitro-phenyl)-carbamic acid tert-butyl ester (Example A14) (8.65 g, 30.6 mmol) by hydrogenation with 10% Pd/C according to the general procedure J (method a). Obtained as a purple solid (6.45 g).

Sources & evidence

ORD record
ord-f4464dadeb604377afa2771d84302fbe
Source dataset
uspto-grants-2005_09
Patent number
US06949542B2

Reaction notes

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