HuagongsheHuagongshe Chemistry Print Report · For research reference only
Stannous chloride dihydrate → [2-Amino-5-(cyclopropyl-methyl-amino)-4-trifluoromethyl-phenyl]-carbamic acid tert-butyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Stannous chloride dihydrate | HCID 61436 | — |
| Reactant | [5-(Cyclopropyl-methyl-amino)-2-nitro-4-trifluoromethyl-phenyl]-carbamic acid tert-butyl ester | HCID 69486640 | — |
| Product | [2-Amino-5-(cyclopropyl-methyl-amino)-4-trifluoromethyl-phenyl]-carbamic acid tert-butyl ester | HCID 69489708 | — |
Reaction Steps
The title compound was prepared from [5-(cyclopropyl-methyl-amino)-2-nitro-4-trifluoromethyl-phenyl]-carbamic acid tert-butyl ester (Example C3) (3.74 g, 9.96 mmol) by reduction with SnCl2.2H2O according to the general procedure J (method b). Obtained as an orange semisolid (2.00 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06949542B2 |
| Source dataset | uspto-grants-2005_09 |
| ORD ID | ord-ca99dae8c3d843808fed4a841a909b03 |
| Source note | uspto-grants-2005_09 |