HuagongsheHuagongshe Chemistry Print Report · For research reference only
(4-Methyl-2-nitro-5-trifluoromethyl-phenyl)-carbamic acid tert-butyl ester → (2-Amino-4-methyl-5-trifluoromethyl-phenyl)-carbamic acid tert-butyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (4-Methyl-2-nitro-5-trifluoromethyl-phenyl)-carbamic acid tert-butyl ester | HCID 69486805 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Product | (2-Amino-4-methyl-5-trifluoromethyl-phenyl)-carbamic acid tert-butyl ester | HCID 69489396 | 87% |
Reaction Steps
Prepared from (4-methyl-2-nitro-5-trifluoromethyl-phenyl)-carbamic acid tert-butyl ester (Example A18) (4.68 g, 14.6 mmol) by hydrogenation with 10% Pd/C according to the general procedure J (method a). Obtained as a white solid (3.68 g, 87%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06949542B2 |
| Source dataset | uspto-grants-2005_09 |
| ORD ID | ord-43be8b0323224b32b648ee39f67ac3ca |
| Source note | uspto-grants-2005_09 |