HCID 69489628, compound → HCID 69489890, compound

HRID 498222Notes

Reaction equation

HRID 498222 reaction equation
[C:1]([O:5][C:6](=[O:25])[NH:7][C:8]1[CH:13]=[C:12]([O:14][CH2:15][CH2:16][CH3:17])[C:11]([C:18]([F:21])([F:20])[F:19])=[CH:10][C:9]=1[N+:22]([O-])=O)([CH3:4])([CH3:3])[CH3:2]>[Pd]>[C:1]([O:5][C:6](=[O:25])[NH:7][C:8]1[CH:13]=[C:12]([O:14][CH2:15][CH2:16][CH3:17])[C:11]([C:18]([F:21])([F:20])[F:19])=[CH:10][C:9]=1[NH2:22])([CH3:2])([CH3:3])[CH3:4]

Participants

3

Reactant 1

HCID 69489628HCID 69489628, compound

Product 1

HCID 69489890HCID 69489890, compound

Reagents, catalysts & solvents 1

HCID 23938PalladiumCatalyst

Procedure

The title compound was prepared from (2-nitro-5-propoxy-4-trifluoromethyl-phenyl)-carbamic acid tert-butyl ester (Example A28) (6.46 g, 17.7 mmol) by hydrogenation with 10% Pd/C according to the general procedure J (method a). Obtained as a white solid (0.93 g, 16%).

Sources & evidence

ORD record
ord-16f5d38be1134941803e06c6f4e242ab
Source dataset
uspto-grants-2005_09
Patent number
US06949542B2

Reaction notes

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