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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 498227Generated: October 30, 2026

HCID 69486618, compound → Carbamic acid,[2-amino-5-[methyl(1-methylethyl)amino]-4-(trifluoromethyl)phenyl]-,1,1-dimethylethyl ester

https://huagongshe.com/reaction/498227

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 69486618HCID 69486618—
CatalystPalladiumHCID 23938—
ProductCarbamic acid,[2-amino-5-[methyl(1-methylethyl)amino]-4-(trifluoromethyl)phenyl]-,1,1-dimethylethyl esterHCID 69486615—

Reaction Steps

The title compound was prepared from [5-(isopropyl-methyl-amino)-2-nitro-4-trifluoromethyl-phenyl]-carbamic acid tert-butyl ester (Example C10) (2.98 g, 7.90 mmol) by hydrogenation with 10% Pd/C according to the general procedure J (method a). Obtained as a orange oil (2.42 g, 88%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06949542B2
Source datasetuspto-grants-2005_09
ORD IDord-a07947d4d69d42128a124dfa60a4a08a
Source noteuspto-grants-2005_09