HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 3-(pyridin-2-yl)benzoate → 3-Oxo-3-(3-pyridin-2-yl-phenyl)-propionic acid tert-butyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 3-(pyridin-2-yl)benzoate | HCID 3364101 | — |
| Reactant | Lithium Tert-butyl Acetate | HCID 86586795 | — |
| Product | 3-Oxo-3-(3-pyridin-2-yl-phenyl)-propionic acid tert-butyl ester | HCID 69489201 | — |
Reaction Steps
The title compond was prepared from 3-pyridin-2-yl-benzoic acid methyl ester [CAS-No. 98061-20-2] (9.42 g, 44.18 mmol) by treatment with lithium tert-butyl acetate according to general procedure K (method b). Obtained as a yellow oil (8.35 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06949542B2 |
| Source dataset | uspto-grants-2005_09 |
| ORD ID | ord-d98e1616698147ef96b0090ae009be8d |
| Source note | uspto-grants-2005_09 |