tert-Butyl acetate → HCID 69486907, compound

HRID 498241Notes

Reaction equation

HRID 498241 reaction equation
CO[C:3](=[O:24])[C:4]1[CH:9]=[CH:8][CH:7]=[C:6]([C:10]2[CH:15]=[CH:14][N:13]=[C:12]([CH2:16][O:17][CH:18]3[CH2:23][CH2:22][CH2:21][CH2:20][O:19]3)[CH:11]=2)[CH:5]=1.[C:25]([O:28][C:29]([CH3:32])([CH3:31])[CH3:30])(=[O:27])[CH3:26]>>[C:29]([O:28][C:25](=[O:27])[CH2:26][C:3](=[O:24])[C:4]1[CH:9]=[CH:8][CH:7]=[C:6]([C:10]2[CH:15]=[CH:14][N:13]=[C:12]([CH2:16][O:17][CH:18]3[CH2:23][CH2:22][CH2:21][CH2:20][O:19]3)[CH:11]=2)[CH:5]=1)([CH3:32])([CH3:31])[CH3:30]

Participants

3

Reactant 2

HCID 10908tert-Butyl acetateHCID 69490018HCID 69490018, compound

Product 1

HCID 69486907HCID 69486907, compound

Procedure

Reaction of (RS)-3-[2-(tetrahydro-pyran-2-yloxymethyl)-pyridin-4-yl]-benzoic acid methyl ester with tert-butyl acetate according to general procedure K (method d; example K8) yielded the title compound as a light yellow oil.

Sources & evidence

ORD record
ord-2d94189f34794edba7324aec2bd72910
Source dataset
uspto-grants-2005_09
Patent number
US06949542B2

Reaction notes

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