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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 498272Generated: November 1, 2026

tert-Butyl (3-amino-2'-fluoro-[1,1'-biphenyl]-4-yl)carbamate → HCID 86589237, compound

https://huagongshe.com/reaction/498272

Reaction equation

Participants

RoleNameHCIDCharge
Reactanttert-Butyl (3-amino-2'-fluoro-[1,1'-biphenyl]-4-yl)carbamateHCID 67361423—
Reactant3-Oxo-3-(3-pyridin-4-yl-phenyl)-propionic acid tert-butyl esterHCID 69486853—
ProductHCID 86589237HCID 86589237—

Reaction Steps

The title compound was prepared from (3-amino-2′-fluoro-biphenyl-4-yl)-carbamic acid tert-butyl ester [CAS-No. 335255-65-7] and 3-oxo-3-(3-pyridin-4-yl-phenyl)-propionic acid tert-butyl ester (Example K2) according to the general procedure M. Obtained as a yellow solid (410 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06949542B2
Source datasetuspto-grants-2005_09
ORD IDord-4acbf93ec2b14caf89c22798ba13f553
Source noteuspto-grants-2005_09