1,1-Dimethylethyl N-(2-amino-4-chlorophenyl)carbamate → HCID 86589238, compound

HRID 498273Notes

Reaction equation

HRID 498273 reaction equation
[C:1]([O:5][C:6](=[O:16])[NH:7][C:8]1[CH:13]=[CH:12][C:11]([Cl:14])=[CH:10][C:9]=1[NH2:15])([CH3:4])([CH3:3])[CH3:2].C([O:21][C:22](=O)[CH2:23][C:24](=[O:37])[C:25]1[CH:30]=[CH:29][CH:28]=[C:27]([C:31]2[CH:36]=[CH:35][N:34]=[CH:33][CH:32]=2)[CH:26]=1)(C)(C)C>>[C:1]([O:5][C:6](=[O:16])[NH:7][C:8]1[CH:13]=[CH:12][C:11]([Cl:14])=[CH:10][C:9]=1[NH:15][C:22](=[O:21])[CH2:23][C:24](=[O:37])[C:25]1[CH:30]=[CH:29][CH:28]=[C:27]([C:31]2[CH:32]=[CH:33][N:34]=[CH:35][CH:36]=2)[CH:26]=1)([CH3:4])([CH3:2])[CH3:3]

Participants

3

Reactant 2

HCID 574562721,1-Dimethylethyl N-(2-amino-4-chlorophenyl)carbamateHCID 694868533-Oxo-3-(3-pyridin-4-yl-phenyl)-propionic acid tert-butyl ester

Product 1

HCID 86589238HCID 86589238, compound

Procedure

Prepared from (2-amino-4-chloro-phenyl)-carbamic acid tert-butyl ester (Example J4) and 3-oxo-3-(3-pyridin-4-yl-phenyl)-propionic acid tert-butyl ester (Example K2) according to the general procedure M. Obtained as a yellow solid (270 mg).

Sources & evidence

ORD record
ord-066323a6c8c54b518a0f5980353d5dcc
Source dataset
uspto-grants-2005_09
Patent number
US06949542B2

Reaction notes

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