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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 498279Generated: October 31, 2026

3-Oxo-3-(3-pyridin-3-yl-phenyl)-propionic acid tert-butyl ester → HCID 86589244, compound

https://huagongshe.com/reaction/498279

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Oxo-3-(3-pyridin-3-yl-phenyl)-propionic acid tert-butyl esterHCID 11266473—
ReactantCarbamic acid,[2-amino-5-(2,2,2-trifluoroethoxy)-4-(trifluoromethyl)phenyl]-,1,1-dimethylethyl esterHCID 76849205—
ProductHCID 86589244HCID 86589244—

Reaction Steps

The title compound was prepared from [2-amino-5-(2,2,2-trifluoro-ethoxy)-4-trifluoromethyl-phenyl]-carbamic acid tert-butyl ester (Example J6) and 3-oxo-3-(3-pyridin-3-yl-phenyl)-propionic acid tert-butyl ester (Example K1) according to the general procedure M. Obtained as a light yellow solid (331 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06949542B2
Source datasetuspto-grants-2005_09
ORD IDord-bd8aa25cb70448938ef26557624a6e05
Source noteuspto-grants-2005_09