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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 498291Generated: October 30, 2026

Carbamic acid,n-[2-amino-5-ethoxy-4-(trifluoromethyl)phenyl]-,1,1-dimethylethyl ester → HCID 86589256, compound

https://huagongshe.com/reaction/498291

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCarbamic acid,n-[2-amino-5-ethoxy-4-(trifluoromethyl)phenyl]-,1,1-dimethylethyl esterHCID 67361421—
Reactant3-Oxo-3-(3-pyridin-2-yl-phenyl)-propionic acid tert-butyl esterHCID 69489201—
ProductHCID 86589256HCID 86589256—

Reaction Steps

The title compound was prepared from (2-amino-5-ethoxy-4-trifluoromethyl-phenyl)-carbamic acid tert-butyl ester (Example J8) (240 mg, 0.75 mmol) and 3-oxo-3-(3-pyridin-2-yl-phenyl)-propionic acid tert-butyl ester (Example K3) (223 mg, 0.75 mmol) according to the general procedure M. Obtained as an off-white solid (234 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06949542B2
Source datasetuspto-grants-2005_09
ORD IDord-da5ae6113de648719a0e6e701b2ef193
Source noteuspto-grants-2005_09