HuagongsheHuagongshe Chemistry Print Report · For research reference only
tert-Butyl (2-amino-4-chloro-5-methylphenyl)carbamate → {4-Chloro-5-methyl-2-[3-oxo-3-(3-pyridazin-4-yl-phenyl)-propionylamino]-phenyl}-carbamic acid tert-butyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | tert-Butyl (2-amino-4-chloro-5-methylphenyl)carbamate | HCID 69486983 | — |
| Reactant | 3-Oxo-3-(3-pyridazin-4-yl-phenyl)-propionic acid tert-butyl ester | HCID 69489514 | — |
| Product | {4-Chloro-5-methyl-2-[3-oxo-3-(3-pyridazin-4-yl-phenyl)-propionylamino]-phenyl}-carbamic acid tert-butyl ester | HCID 86589260 | — |
Reaction Steps
The title compound was prepared from (2-amino-4-chloro-5-methyl-phenyl)-carbamic acid tert-butyl ester (Example J22) and 3-oxo-3-(3-pyridazin-4-yl-phenyl)-propionic acid tert-butyl ester (Example K9) according to the general procedure M. Obtained as a light yellow solid (184 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06949542B2 |
| Source dataset | uspto-grants-2005_09 |
| ORD ID | ord-5bcd916ab7a240ab9620bc3c96b92c48 |
| Source note | uspto-grants-2005_09 |