tert-Butyl (2-amino-4-chloro-5-fluorophenyl)carbamate → {4-Chloro-5-fluoro-2-[3-oxo-3-(3-pyridin-2-yl-phenyl)-propionylamino]-phenyl}-carbamic acid tert-butyl ester

Participants

Reaction Steps

The title compound was prepared from (2-amino-4-chloro-5-fluoro-phenyl)-carbamic acid tert-butyl ester (Example J5) (205 mg, 0.79 mmol) and 3-oxo-3-(3-pyridin-2-yl-phenyl)-propionic acid tert-butyl ester (Example K3) (302 mg, 0.97 mmol) according to the general procedure M. Obtained as a pink foam (340 mg).

Provenance & Evidence