3-Oxo-3-(3-pyridin-4-yl-phenyl)-propionic acid tert-butyl ester → [2-[3-Oxo-3-(3-pyridin-4-yl-phenyl)-propionylamino]-5-(2,2,2-trifluoro-ethoxy)-phenyl]-carbamic acid tert-butyl ester

Beteiligte Stoffe

Rolle	Name	HCID	Einwaage
Edukt	3-Oxo-3-(3-pyridin-4-yl-phenyl)-propionic acid tert-butyl ester	HCID 69486853	—
Edukt	Carbamic acid,[2-amino-5-(2,2,2-trifluoroethoxy)phenyl]-,1,1-dimethylethyl ester	HCID 69487918	—
Produkt	[2-[3-Oxo-3-(3-pyridin-4-yl-phenyl)-propionylamino]-5-(2,2,2-trifluoro-ethoxy)-phenyl]-carbamic acid tert-butyl ester	HCID 86589266	—

Reaktionsschritte

The title compound was prepared from [2-amino-5-(2,2,2-trifluoro-ethoxy)-phenyl]-carbamic acid tert-butyl ester (Example J13) (230 mg, 0.75 mmol) and 3-oxo-3-(3-pyridin-4-yl-phenyl)-propionic acid tert-butyl ester (Example K2) (223 mg, 0.75 mmol) according to the general procedure M. Obtained as a light brown solid (258 mg).

Herkunft & Nachweise

DOI	10.6084/m9.figshare.5104873.v1
Patentnummer	US06949542B2
Quelldatensatz	uspto-grants-2005_09
ORD ID	ord-4229bf3121e945009e18cc7bac419762
Quellennotiz	uspto-grants-2005_09